Biochemistry PASS / LAS (Pre-Med) Revision Sheets
Biochemistry is part of UE1 of the PASS curriculum (Atoms, Biomolecules, Genome, Bioenergetics, Metabolism) and carries one of the highest coefficients on the concours. It combines organic chemistry and molecular biology to understand the reactions of life.
Biochemistry curriculum in PASS / LAS (Pre-Med)
The curriculum covers the structure and function of biomolecules (carbohydrates, lipids, proteins, nucleic acids), enzymes and enzyme kinetics, bioenergetics (ATP, redox), and intermediary metabolism (glycolysis, Krebs cycle, oxidative phosphorylation, fatty acid β-oxidation). Hormonal regulation of metabolism and metabolic disorders are also addressed.
How to study biochemistry in PASS / LAS (Pre-Med)?
3 simple steps for effective biochemistry revision.
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Tips to succeed in biochemistry PASS / LAS (Pre-Med)
Learn metabolic pathways by redrawing the full pathway from memory before checking notes — it's the most effective anchoring technique
Understand the energy logic (ATP yield per step) instead of rote memorizing molecules: the concours frequently tests balances
Build comparison sheets glycolysis/gluconeogenesis, β-oxidation/lipogenesis to spot key enzymes and regulation points
Do at least 500 biochemistry MCQs before the concours: it's the UE where intensive drill pays off the most in score gain
FAQ — Biochemistry PASS / LAS (Pre-Med)
Which biochemistry chapters are highest-yield in PASS?
Highest points-per-hour chapters are enzyme kinetics (short formulas, signature diagrams), glycolysis and Krebs cycle (always tested), and hormonal regulation of metabolism. Amino acid structure and proteins also feature heavily. Master these four chapters before tackling the rest.
How do I remember all metabolic pathways in PASS biochemistry?
The most effective technique is active reconstruction: take a blank sheet, redraw the full pathway with enzymes, cofactors and energy balances. Repeat every 3 days. In two weeks you memorize glycolysis, Krebs, β-oxidation and gluconeogenesis effortlessly. FSRS flashcards complement this method well for details (Km, Vmax, inhibitors).
Are there must-know formulas in PASS biochemistry?
Yes, a few formulas appear almost systematically: Michaelis-Menten (v = Vmax × [S] / (Km + [S])), Km/Vmax calculation via Lineweaver-Burk plots, glycolysis net yield (2 ATP), Krebs cycle yield (1 GTP, 3 NADH, 1 FADH2 per turn), and the total ATP yield of glucose oxidation (36-38 ATP depending on the shuttle).
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