Thermodynamic System — types?
Isolated, adiabatic, closed, and open.
Isolated system — exchange?
No matter or energy exchange.
Open system — exchange?
Both matter and energy exchange.
Cell as open system — role?
Exchanges matter, energy, info to maintain homeostasis.
Intensive variables — examples?
Pressure, temperature, potential.
Extensive variables — examples?
Volume, moles, total energy.
First law — equation?
dU = dQ + dW, energy conserved.
Cell metabolism — law?
Follows first law; energy transforms, conserved.
Electrochemical potential — driver?
Ion movement across membranes.
Flux coupling — concept?
Interconnected transfer of matter, energy, info.
Fick's first law — describes?
Diffusion flux proportional to concentration gradient.
Fick's second law — describes?
Change in concentration over time.
Water movement — driven by?
Osmotic and hydrostatic pressures.
Osmosis — movement?
Water across semi-permeable membrane, low to high solute.
Electrolyte diffusion — equilibrium?
Net ionic flux zero at equilibrium potential.
Membrane permeability — depends on?
Membrane structure and molecule properties.
Ion channels — properties?
Selective, gated, conduct ionic currents.
Active transport — energy?
Requires energy input, moves against gradient.
Primary active transport — example?
Ca2+-ATPase, proton pump.
Epithelial transport — mechanisms?
Passive diffusion, facilitated, active, co-transport.
Тествайте знанията си с 10 въпроса по Cellular Transport and Thermodynamics.
1. What is an open thermodynamic system?
2. Who initially conceptualized the cell as an open thermodynamic system in the 1960s?
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