Pancreatic islets — cell types?
β-cells produce insulin; α-cells produce glucagon.
Islets of Langerhans
Small pancreatic clusters secreting hormones
Proinsulin — domains?
α-chain, β-chain, C-peptide.
Insulin primary producer
Produced by β-cells
Glucagon producer
Produced by α-cells
Proinsulin parts
β-chain, α-chain, C-peptide
Insulin release pattern
Biphasic: quick and sustained
Insulin actions
Lowers blood glucose and promotes storage
Blood glucose regulation
Insulin decreases, glucagon increases blood sugar
Тествайте знанията си с 11 въпроса по Hormonal Regulation of Blood Glucose.
1. Which pancreatic islet cell type produces and secretes insulin?
2. What are the small pancreatic cell clusters called that perform endocrine hormone secretion?
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