ADR — definition?
Unintended, harmful response at normal doses.
ADR — definition?
Unintended, noxious response to drug at normal doses.
ADR & mechanism — role?
Results from pharmacodynamic or pharmacokinetic factors.
Side Effect — difference?
Related to pharmacology; can be beneficial, neutral, or harmful.
Side effects — properties?
Related to drug's pharmacology; may be beneficial or neutral.
ADE — definition?
Adverse outcome post-drug use; includes all ADRs.
Type A ADR — characteristics?
Predictable, dose-dependent, common, preventable.
Type B ADR — characteristics?
Unpredictable, not dose-dependent, often serious.
Factors influencing susceptibility?
Age, gender, genetics, co-morbidities, polypharmacy.
Immunological reactions — example?
Allergic reactions like rashes, anaphylaxis.
Test your knowledge with 10 questions on Understanding Adverse Drug Reactions and Susceptibility.
1. What is an adverse drug reaction (ADR)?
2. According to the WHO definition, an adverse drug reaction (ADR) occurs under what conditions?
Review the complete course in the revision sheet for Understanding Adverse Drug Reactions and Susceptibility.
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