Flashcard: Sympathetic Nervous System Pharmacology — 16 carte

Sympathetic Nervous System — role?

Regulates involuntary organ functions during stress.

Neurotransmitters — main types?

Noradrenaline and adrenaline.

Adrenergic Receptors — types?

α1, α2, β1, β2, β3.

Sympathomimetic drugs — mechanism?

Activate adrenergic receptors directly or indirectly.

Sympatholytic drugs — action?

Block or inhibit sympathetic activity.

α1 receptor effect?

Vasoconstriction and mydriasis.

β2 receptor effect?

Bronchodilation and vasodilation.

Adrenaline — clinical use?

Anaphylaxis, cardiac arrest, severe hypotension.

Noradrenaline — primary indication?

Shock and severe hypotension.

Dopamine — dose effects?

Low: renal vasodilation; high: cardiac and vasoconstriction.

α1 agonists — example?

Phenylephrine.

β2 agonists — example?

Salbutamol.

α blockers — example?

Prazosin.

β blockers — example?

Propranolol.

Drug interaction — with MAO inhibitors?

Enhances sympathomimetic effects, risk of hypertensive crisis.

Drug interaction — with β blockers?

Can diminish sympathomimetic effects or cause adverse reactions.