Flashcards: Candida Infections: Forms, Pathogenesis, and Manifestations — 20 cartões

Candida albicans — forms?

Yeast, pseudohyphae, chlamydospore.

Other Candida species — involved?

C. tropicalis, C. parapsilosis, C. stellatoidea, C. krusei, C. guilliermondii, C. dubliniensis, C. glabrata.

Candida growth temperature?

25–37°C.

Identification methods?

Pseudohyphae formation and biochemical tests.

Pseudohyphae — significance?

Diagnostic feature indicating pathogenic Candida.

Candida reproduction?

Asexually by budding.

Yeast to hyphae — process?

Transformation linked to pathogenicity.

Forms of Candida?

Yeast, pseudohyphae, chlamydospore.

Pathogenesis factor — tissue invasion?

Required for disease manifestation.

Host defenses — key components?

Salivary IgA, T cells, neutrophils.

Predisposing condition — antibiotics?

Disrupt normal flora, promote overgrowth.

Predisposing condition — immunosuppression?

Reduces host defenses, increases susceptibility.

Main clinical form — pseudomembranous?

White plaques that can be wiped off.

Main clinical form — erythematous?

Red, painful mucosal patches.

Main clinical form — hyperplastic?

Persistent white plaques, possibly premalignant.

Pseudomembranous candidiasis — also called?

Thrush.

Erythematous candidiasis — common site?

Dorsal tongue, palate.

Chronic hyperplastic candidiasis — features?

White, keratotic plaques resistant to treatment.

Candida invasion — requires?

Transformation to hyphal form.

Key immune factor preventing adherence?

Salivary IgA.