Karteikarten: Beta-Lactam Antibiotics: Structure, Spectrum, Resistance — 9 Karten

β Lactam antibiotics — core feature?

Contain a strained β lactam ring essential for activity.

β Lactam ring — essential feature?

Four-membered lactam ring, crucial for activity.

Penicillins — origin?

Derived from *Penicillium* molds, mainly *P. notatum* and *P. chrysogenum*.

Penicillins — origin?

Derived from Penicillium fungi.

Cephalosporins — structural difference?

Different core structure from penicillins.

Monobactams — key feature?

Single β lactam ring, no fused rings.

Carbapenems — activity?

Broad-spectrum, stable, potent antibiotics.

PBPs — role?

Targeted by β lactam antibiotics, inhibit cell wall synthesis.

Resistance — main mechanism?

β lactamase enzymes breaking down antibiotics.