Cancer hallmarks — definition?
Biological traits enabling tumor growth and spread.
Cancer hallmarks — definition?
Biological capabilities enabling tumor growth and spread.
Cell cycle dysregulation — mechanism?
Mutations in genes controlling cell division lead to uncontrolled proliferation.
Sustaining proliferative signaling — role?
Allows continuous growth stimulation in cancer cells.
Tumor microenvironment — components?
Includes stromal cells, immune cells, ECM, and signaling molecules.
Evading growth suppressors — example?
Inactivation of p53 or RB.
Resisting cell death — mechanism?
Avoiding apoptosis through pathway mutations.
Enabling replicative immortality — factor?
Telomerase activation maintains telomeres.
Angiogenesis — process?
Tumors stimulate new blood vessel formation.
Invasion and metastasis — ability?
Cancer spreads to distant sites.
Test your knowledge with 10 questions on Cancer Biology Essentials.
1. What are the 'Hallmarks of Cancer' as described in cancer biology?
2. Who were the scientists that initially proposed the six hallmarks of cancer?
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