Flashcards: Leukocyte Disorders and Blood Cell Dynamics — 14 cards

Leukocytes — definition?

White blood cells vital for immunity.

Innate vs acquired — role?

Innate provides immediate defense; acquired offers targeted response.

Haemopoietic stem cell — origin?

Origin of all white blood cells in bone marrow.

Colony-stimulating factors — function?

Stimulate leukocyte maturation and proliferation.

Peripheral blood smear — classification?

Polymorphonuclear (granulocytes) and mononuclear (agranulocytes).

WBC normal age shift?

Lymphocytes predominate in children; neutrophils in adults.

WBC count — leukopaenia?

Less than 3.0 x 10^9/L indicates decreased WBCs.

Leukocytosis — definition?

WBC count above 11 x 10^9/L.

Pancytopaenia — affected cells?

Decreased WBCs, RBCs, and platelets.

Neutrophilia — cause?

Reactive response to infection or inflammation.

Neutropaenia — cause?

Drug effects, infections, or congenital disorders.

Eosinophilia — cause?

CHINA: Connective tissue, Helminths, Idiopathic, Neoplasms, Allergies.

Lymphocytosis — cause?

Viral infections or lymphoid malignancies.

Leukocyte disorder — importance?

Reflects immune status and guides diagnosis.