Temporal Organization of Immune Responses

📋 Course Outline

1. Immune System Missions
2. Sources of Aggression
3. Innate and Adaptive Defense
4. Timing of Immune Responses
5. Strengths and Weaknesses
6. Building Adaptive Immunity
7. Lymphocyte Effectors and Control

📖 1. Immune System Missions

🔑 Key Concepts & Definitions

• Immune system : The set of cellular and molecular mechanisms that protect the organism and support its survival in its environment.

★ Must-know

• The immune system has four major missions:
  • Protect the organism from aggression
  • Avoid attacking the organism and beneficial components through immune tolerance
  • Contribute to tissue repair
  • Protect against a later attack through immune memory

Further detail

• The intestinal microbiota can be beneficial because it produces vitamins and its loss can increase the risk of chronic disease.

💡 Memory Hook

Protect, tolerate, repair, remember: PTRM

📖 2. Sources of Aggression

★ Must-know

• External aggressors include:
  • Infectious agents
  • Toxins
  • Trauma

Further detail

• Infectious agents include:
  • Viruses
  • Bacteria
  • Parasites

💡 Memory Hook

External aggressors enter from outside, whereas internal aggressors arise within the organism