★ Must-know
📌 The substrate is the substance acted on by an enzyme, and it binds at the enzyme’s active site.
Further detail
1. Which enzyme is the rate-limiting step of ketogenesis?
2. Why is the lagging strand synthesized as Okazaki fragments?
3. Which reaction is catalyzed irreversibly by the pyruvate dehydrogenase complex in the mitochondrial matrix?
What is an enzyme?
A biological catalyst that increases reaction rate without being consumed.
What is the substrate in enzyme catalysis?
The substance acted on by an enzyme.
Where does the substrate bind on an enzyme?
At the enzyme’s active site.
What does the lock-and-key model state about the active site?
It is already complementary to the substrate.
What happens in the induced-fit model when substrate binds?
The enzyme’s conformation changes.
How many enzyme classes are there?
Six enzyme classes.
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