Leukocytes — definition?
White blood cells vital for immunity.
Innate vs acquired — role?
Innate provides immediate defense; acquired offers targeted response.
Haemopoietic stem cell — origin?
Origin of all white blood cells in bone marrow.
Colony-stimulating factors — function?
Stimulate leukocyte maturation and proliferation.
Peripheral blood smear — classification?
Polymorphonuclear (granulocytes) and mononuclear (agranulocytes).
WBC normal age shift?
Lymphocytes predominate in children; neutrophils in adults.
WBC count — leukopaenia?
Less than 3.0 x 10^9/L indicates decreased WBCs.
Leukocytosis — definition?
WBC count above 11 x 10^9/L.
Pancytopaenia — affected cells?
Decreased WBCs, RBCs, and platelets.
Neutrophilia — cause?
Reactive response to infection or inflammation.
Neutropaenia — cause?
Drug effects, infections, or congenital disorders.
Eosinophilia — cause?
CHINA: Connective tissue, Helminths, Idiopathic, Neoplasms, Allergies.
Lymphocytosis — cause?
Viral infections or lymphoid malignancies.
Leukocyte disorder — importance?
Reflects immune status and guides diagnosis.
Teste dein Wissen mit 7 Fragen zu Leukocyte Disorders and Blood Cell Dynamics.
1. Who is credited with discovering or proposing colony-stimulating factors that regulate leukocyte development?
2. What is a key distinguishing feature of polymorphonuclear leukocytes compared to mononuclear leukocytes?
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