Flashcard: Kidney Structure and Function Fundamentals — 24 carte

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1Domanda

Kidney regions — main zones?

Risposta

Cortex and medulla.

2Domanda

Renal sinus — role?

Risposta

Receives renal pelvis and calyces.

3Domanda

Hilus — function?

Risposta

Entry/exit point for vessels and ducts.

4Domanda

Cortex — location?

Risposta

Outer kidney zone.

5Domanda

Medulla — location?

Risposta

Inner kidney zone.

6Domanda

Nephron — basic unit?

Risposta

Filtration and reabsorption structure.

7Domanda

Renal corpuscle — what?

Risposta

Glomerulus + Bowman’s capsule.

8Domanda

Glomerulus — function?

Risposta

Filters blood plasma.

9Domanda

Afferent arteriole — role?

Risposta

Supplies blood to glomerulus.

10Domanda

Efferent arteriole — role?

Risposta

Drains blood from glomerulus.

11Domanda

Filtration barrier — layers?

Risposta

Endothelium, basement membrane, podocytes.

12Domanda

Filtration size limit?

Risposta

≤68,000 molecular weight.

13Domanda

GFR — normal rate?

Risposta

125 mL/min or 180 L/day.

14Domanda

Renal blood flow — relation?

Risposta

Flow = Pressure / Resistance.

15Domanda

Autoregulation range?

Risposta

80–180 mmHg arterial pressure.

16Domanda

Tubuloglomerular feedback — sensor?

Risposta

Macula densa Na+ sensing.

17Domanda

Neural GFR control — mechanism?

Risposta

Sympathetic vasoconstriction.

18Domanda

Hormonal GFR control — factors?

Risposta

Angiotensin II, ANP, prostaglandins.

19Domanda

Proximal tubule — water reabsorption?

Risposta

Isosmotic, ~65% reabsorbed.

20Domanda

Loop of Henle — descending limb?

Risposta

Water-permeable, Na–Cl-impermeable.

21Domanda

Loop of Henle — ascending limb?

Risposta

Water-impermeable, Na–Cl passively/actively reabsorbed.

22Domanda

Reabsorption — passive vs active?

Risposta

Passive follows gradients; active uses ATP.

23Domanda

Glomerulotubular balance — purpose?

Risposta

Matches reabsorption to GFR.

24Domanda

Inulin clearance — use?

Risposta

Estimate GFR.

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1. Which structure is the shallow C-shaped space that receives the renal pelvis and calyces through the hilus?

2. Which kidney region is the outer reddish-brown zone that contains mainly convoluted proximal and distal tubules?

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