Flashcards: Immunosuppressants and Chemotherapy Strategies — 10 cards

Immunosuppressant Classes

Drugs that inhibit immune activity for transplantation or autoimmune diseases.

Immunosuppressants — definition?

Drugs that inhibit immune activity.

Chemotherapy Mechanisms

Agents disrupt DNA, mitosis, or specific pathways in cancer cells.

Calcineurin inhibitors — role?

Block T-cell activation by inhibiting IL-2.

Immune System Components

Includes innate and adaptive immunity with lymphocytes, antigens, cytokines.

Antimetabolites — mechanism?

Interfere with nucleotide synthesis.

mTOR inhibitors — effect?

Reduce T-cell proliferation and angiogenesis.

Chemotherapy — primary mechanism?

Damages DNA to kill dividing cells.

Alkylating agents — action?

Cause DNA cross-linking and strand breaks.

Antimetabolites — example?

Methotrexate.