Flashcards: Understanding Drug Interactions — 10 cartões

Drug Interaction Types — main categories?

Pharmacokinetic and pharmacodynamic.

Drug Interaction Types — categories?

Pharmacokinetic and pharmacodynamic.

Pharmacokinetic Mechanisms — influence?

Absorption, distribution, metabolism, excretion.

Pharmacokinetic interaction — effect?

Alters drug absorption, distribution, metabolism, excretion.

Pharmacodynamic Mechanisms — effect?

Drug effects at receptor sites.

Pharmacodynamic interaction — effect?

Influences drugs' effects at action sites.

Enzyme induction — outcome?

Increases metabolism, reducing drug levels.

Enzyme inhibition — outcome?

Decreases metabolism, raising drug levels.

Protein binding displacement — consequence?

Increases active free drug levels.

Narrow therapeutic index — significance?

Increases risk of toxicity or failure.